Calculating a Continuous Metabolic Syndrome Score Using Nationally Representative Reference Values

OBJECTIVE: The prevalence of metabolic syndrome in youth varies on the basis of the classification system used, prompting implementation of continuous scores; however, the use of these scores is limited to the sample from which they were derived. We sought to describe the derivation of the continuou...

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Published inAmbulatory pediatrics : the official journal of the Ambulatory Pediatric Association Vol. 18; no. 5; p. 589
Main Authors Guseman, Emily Hill, Eisenmann, Joey C, Laurson, Kelly R, Cook, Stephen R, Stratbucker, William
Format Journal Article
LanguageEnglish
Published Lawrence Elsevier Science Ltd 01.07.2018
Subjects
Mathematical analysis
Metabolic syndrome
Obesity
Pediatrics
Teenagers
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Summary:OBJECTIVE: The prevalence of metabolic syndrome in youth varies on the basis of the classification system used, prompting implementation of continuous scores; however, the use of these scores is limited to the sample from which they were derived. We sought to describe the derivation of the continuous metabolic syndrome score using nationally representative reference values in a sample of obese adolescents and a national sample obtained from National Health and Nutrition Examination Survey (NHANES) 2011-2012. METHODS: Clinical data were collected from 50 adolescents seeking obesity treatment at a stage 3 weight management center. A second analysis relied on data from adolescents included in NHANES 2011-2012. performed for illustrative purposes. The continuous metabolic syndrome score was calculated by regressing individual values onto nationally representative age- and sex-specific standards (NHANES 111). Resultant z scores were summed to create a total score. RESULTS: The final sample included 42 obese adolescents (15 male and 35 female subjects; mean age, 14.8 + 1.9 years) and an additional 445 participants from NHANES 2011-2012. Among the clinical sample, the mean continuous metabolic syndrome score was 4.16 ± 4.30, while the NHANES sample mean was quite a bit lower, at -0.24 ± 2.8. CONCLUSIONS: We provide a method to calculate the continuous metabolic syndrome by comparing individual risk factor values to age- and sex-specific percentiles from a nationally representative sample.
ISSN:1876-2859
1876-2867