SUDDEN DEATH IN EPILEPSY: CASE REPORT AND LITERATURE REVIEW

According to Lhatoo and Sander (2002), the mortality rate among epileptics is 2 to 5 times higher compared to the general population, 40% of being related to epilepsy [5]. Sheline et al. have tried to explain for the first time the link between epilepsy and depression, the common denominator being c...

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Published inInternational journal of medical dentistry Vol. 7; no. 4; pp. 253 - 260
Main Authors Hunea, Iuliana, Knieling, Anton, Iov, Cătălin J, Rîşcanu, Laura, David, Sofia, Ciuhodaru, Octavia, Iliescu, Diana Bulgaru
Format Journal Article
LanguageEnglish
Published Iasi Apollonia University of Iasi, Medical Dentistry Faculty 01.10.2017
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Summary:According to Lhatoo and Sander (2002), the mortality rate among epileptics is 2 to 5 times higher compared to the general population, 40% of being related to epilepsy [5]. Sheline et al. have tried to explain for the first time the link between epilepsy and depression, the common denominator being changes in the vegetative system. [...]in patients with depression, a decrease in hippocampal size relatively to the control group was identified. [...]central apnea will lead to exitus, both directly and indirectly, with acidosis, followed by hyperpotassemia, with fatal malignant arrhythmias (torsade de pointes). On cross-sections, especially in the lower left ventricular wall, subendocardia, white-pearly streaks with reduced elasticity are lost among the myocardial fibers; Macroscopic diagnoses: infiltrated epicranian hemorrhage; cortical atrophy; pulmonary edema; miocardo-sclerossis; A toxicological and histopathological examination was performed, evidencing the presence of barbiturates - phenobarbital 135.4 pg/ml (therapeutic dose), beclamide - anticonvulsant (barrel, bile, liver, stomach and gastric contents, kidneys) indicating a toxic dose; no pesticides, carbamate, organophosphorus, organochlorine, toxic, benzodiazepine, TCA, ethyl alcohol, methyl alcohol, drugs have been identified.
ISSN:2066-6063
2392-8018