Antibacterial activity of the ethanolic extract of the petiole from Rheum rhabarbarum

Natural products have a wide variety of biological activities that allow us to find new therapeutic alternatives. In this work, the in vitro antibacterial activity of the ethanol extract of the petiole of Rheum rhabarbarum against ATCC strains of Staphylococcus aureus, Staphylococcus epidermidis, Kl...

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Published inRevista colombiana de ciencias químico-farmacéuticas Vol. 47; no. 1; p. 26
Main Authors Nerlis, Paola Pájaro, Clemente Granados Conde, Miladys Esther Torrenegra Alarcón
Format Journal Article
LanguageSpanish
Published Bogota Universidad Nacional de Colombia 01.01.2018
Subjects
Antimicrobial agents
Bacteria
E coli
Ethanol
Flowers & plants
Klebsiella
Natural products
Pseudomonas aeruginosa
Staphylococcus infections
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Summary:Natural products have a wide variety of biological activities that allow us to find new therapeutic alternatives. In this work, the in vitro antibacterial activity of the ethanol extract of the petiole of Rheum rhabarbarum against ATCC strains of Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli was evaluated, determining the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (CMB). To solubilize, 1%dimethylsulfoxide (DMSO) was used. The results show that the extract has antibacterial activity, with MIC values ≥ 700 μg/mL for the ethanolic extract against Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumoniae, Pseudomonasaeruginosa and Escherichia coli. Its effect could be bacteriostatic and not bactericidal. Therefore, it is concluded that the plant species Rheum rhabarbarum is consideredpromising for bacterial control.
ISSN:0034-7418
1909-6356
DOI:10.15446/rcciquifa.v47n1.70656