Differential effects of pertussis toxin on the muscarinic regulation of Ca2positive and Kpositive currents in frog cardiac myocytes

The ability of acetylcholine (ACh) to inhibit beta-agonist stimulated calcium current was compared to its ability to activate the inwardly rectifying potassium current IK(ACh) in frog atrial myocytes. ACh inhibited the calcium current at concentrations significantly lower than those required for the...

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Bibliographic Details
Published inThe Journal of general physiology Vol. 104; no. 5; p. 941
Main Authors Li, Yongxin, Hanf, Remy, Otero, Angela S, Fischmeister, Rodolphe, Szabo, Gabor
Format Journal Article
LanguageEnglish
Published New York Rockefeller University Press 01.11.1994
Subjects
Calcium
Cellular biology
Electricity
Heart
Reptiles & amphibians
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Summary:The ability of acetylcholine (ACh) to inhibit beta-agonist stimulated calcium current was compared to its ability to activate the inwardly rectifying potassium current IK(ACh) in frog atrial myocytes. ACh inhibited the calcium current at concentrations significantly lower than those required for the activation of IK(ACh).
ISSN:0022-1295
1540-7748