Lipid modifications of G proteins: (Alpha) subunits are palmitoylated

Covalent lipid modifications are found on both the alpha and gamma subunits of heterotrimeric, signal-transducing, guanine nucleotide-binding proteins, and in an effort to identify posttranslational modifications of alphas and alphaq, alpha subunits were examined for incorporation of radioactive pal...

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Bibliographic Details
Published inProceedings of the National Academy of Sciences - PNAS Vol. 90; no. 8; p. 3675
Main Authors Linder, Maurine E, Middleton, Pamela, Hepler, John R, Taussig, Ronald
Format Journal Article
LanguageEnglish
Published Washington National Academy of Sciences 15.04.1993
Subjects
Biochemistry
Pharmacology
Proteins
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Summary:Covalent lipid modifications are found on both the alpha and gamma subunits of heterotrimeric, signal-transducing, guanine nucleotide-binding proteins, and in an effort to identify posttranslational modifications of alphas and alphaq, alpha subunits were examined for incorporation of radioactive palmitate. Results are discussed.
ISSN:0027-8424
1091-6490