Extensive peptide ligand exchange by surface class I major histocompatibility complex molecules independent of exogenous (beta)(2)-microglobulin

The surface binding and disassociation of two virus-derived ligands of the L(d) class I molecule of the mouse were compared in a study. The results demonstrate the potential for surface class I molecules to undergo peptide ligand exchange independent of exogenous beta2-microglobulin.

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Bibliographic Details
Published inProceedings of the National Academy of Sciences - PNAS Vol. 89; no. 16; p. 7767
Main Authors Smith, Joseph D, Wen-Rong Lie, Gorka, John, Myers, Nancy B, Hansen, Ted H
Format Journal Article
LanguageEnglish
Published Washington National Academy of Sciences 15.08.1992
Subjects
Immunity (Disease)
Medical research
Molecules
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Summary:The surface binding and disassociation of two virus-derived ligands of the L(d) class I molecule of the mouse were compared in a study. The results demonstrate the potential for surface class I molecules to undergo peptide ligand exchange independent of exogenous beta2-microglobulin.
ISSN:0027-8424
1091-6490