Therapeutic effects of intraoprative placement of chemotherapy pump and postoperative local infusion of chemotherapeutic drug for breast cancer

Objective To observe the effects of postoperative adjuvant local chemotherapy on the prognosis of the patients with breart cancer,and explore the skill of intraoperative placement of a catheter for postoperative chemotherapy duning the operation.Methods Of 102 patients with breast cancer in stage Ⅱ...

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Published inJie fang jun yi xue za zhi Vol. 36; no. 10; p. 1098
Main Authors QIN, Rong, Yong-dong, PU, YANG, Bo, Jian-miao HE, Li-guo, DONG, Zhi-yu, CAO, LV, Gang, LIU, Wei-ping, You-jun, WU
Format Journal Article
LanguageChinese
Published Beijing People's Military Medical Press 01.01.2011
Subjects
Biopsy
Breast cancer
Cancer therapies
Chemotherapy
Drug dosages
Surgery
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Summary:Objective To observe the effects of postoperative adjuvant local chemotherapy on the prognosis of the patients with breart cancer,and explore the skill of intraoperative placement of a catheter for postoperative chemotherapy duning the operation.Methods Of 102 patients with breast cancer in stage Ⅱ to Ⅲ,23 were assigned to control group and 79 to catheter and pump-placement group.Quadrantectomy plus axillary lymph node dissection or modified radical mastectomy was performed in both groups,followed by the insertion of a catheter for pumping of chemotherapeutic drug in pump-placement group.The catheter was inserted into axillary artery through the lateral thoracic artery or subscapular artery,connecting with a chemotherapy pump for instillation of chemotherapeutic drug and it was fixed on the skin for local adjuvant chemotherapy thereafter.The catheter was washed with heparin once a week to prevent occlusion.10-14 days after surgery,patients in pump-placement group underwent local chemotherapy with 5-FU at a do
ISSN:0577-7402