Efficacy of nutrition therapy in patients with alcoholic liver diseases: a meta-analysis

Objective　To evaluate the efficacy of nutrition therapy in alcoholic liver diseases (ALD). Methods　PubMed, Embase, Web of Science, The Cochrane Central Register of Controlled Trials, Chinese Journals Full-Text Database, Chinese Biomedical Database and Wan Fang Digital Journal Full-Text Database were...

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Bibliographic Details
Published inJie fang jun yi xue za zhi Vol. 40; no. 11; p. 927
Main Authors Cai-qun BIE, Sheng-lan, WU, Shao-hui, TANG
Format Journal Article
LanguageChinese
Published Beijing People's Military Medical Press 01.01.2015
Subjects
Dietitians
Full text databases
Liver diseases
Meta-analysis
Mortality
Nutrition
Phosphatase
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Summary:Objective　To evaluate the efficacy of nutrition therapy in alcoholic liver diseases (ALD). Methods　PubMed, Embase, Web of Science, The Cochrane Central Register of Controlled Trials, Chinese Journals Full-Text Database, Chinese Biomedical Database and Wan Fang Digital Journal Full-Text Database were searched for relevant articles. Statistical analysis was performed by meta-analysis using Review Manager 5.1.0. Results　Twelve randomized controlled trials including 508 cases were analyzed. Meta-analysis results were as follows: Compared with conventional therapy, nutrition therapy was more effective in reducing the serum total bilirubin (P=0.04) and alkaline phosphatase (P=0.04), and increasing serum transferrin (P＜0.00001), but there was no statistically significant difference between the two groups in other liver functions and complications associated with ALD. There was no statistically significant difference between the two groups in the incidence of infection, short-term or long-term mortality of ALD. Concl
ISSN:0577-7402
DOI:10.11855/j.issn.0577-7402.2015.11.14