D12 MECHANISMS OF ALLERGIC AIRWAY INFLAMMATION: The Unfolded Protein Response Is An Essential Regulator Of Airway Inflammatory Responses In A Murine Model Of Allergic Asthma

[...]TUDCA mediated decreases in the UPR protect from allergen-induced allergic airway responses. [...]specific UPR-related mediators are potential targets to inhibit cytokine production in effector T cell populations.

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Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 195
Main Authors Nakada, E M, Siddesha, J M, Korwin-Mihavics, B R, Chamberlain, N L, Bruno, S R, Chapman, D G, Ather, J L, Irvin, C G, Dixon, A E, Poynter, M E, Anathy, V
Format Journal Article
LanguageEnglish
Published New York American Thoracic Society 01.01.2017
Subjects
Asthma
Cytokines
Inflammation
Rodents
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Summary:[...]TUDCA mediated decreases in the UPR protect from allergen-induced allergic airway responses. [...]specific UPR-related mediators are potential targets to inhibit cytokine production in effector T cell populations.
ISSN:1073-449X
1535-4970