A13 ROLE OF DYSBIOSIS IN LUNG DISEASE: Lung Microbiota Are Altered In A Murine Model Of Pulmonary Fibrosis And Are Necessary For Pathogenesis
Rationale: The pathophysiology of Idiopathic Pulmonary Fibrosis (IPF), a fatal interstitial lung disease, is poorly understood. When germ-free mice were challenged with bleomycin instillation, they did not develop pulmonary fibrosis as assessed by hydroxyproline concentration.
Saved in:
Published in | American journal of respiratory and critical care medicine Vol. 195 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
American Thoracic Society
01.01.2017
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Rationale: The pathophysiology of Idiopathic Pulmonary Fibrosis (IPF), a fatal interstitial lung disease, is poorly understood. When germ-free mice were challenged with bleomycin instillation, they did not develop pulmonary fibrosis as assessed by hydroxyproline concentration. |
---|---|
ISSN: | 1073-449X 1535-4970 |