D109 UNDERSTANDING THE MECHANISMS OF ACUTE LUNG INJURY: Personalized Mechanical Ventilation Strategy Minimizes Ventilator-Induced Lung Injury In Experimental Acute Respiratory Distress Syndrome

In patients with acute respiratory distress syndrome (ARDS), improper mechanical ventilation settings can cause a secondary ventilator-induced lung injury (VILI). Amphiregulin (p=0.04) and vascular cell adhesion molecule (VCAM)-1 (p=0.04) mRNA expression was higher in VCV than NV, with no significan...

Full description

Saved in:
Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 195
Main Authors Silva, P L, Cruz, F F, Samary, C S, Moraes, L, Magalhães, R, Fernandes, M V, Bose, R, Capelozzi, V L, Satalin, J, Gatto, L A, Andrews, P, Habashi, N, Nieman, G, Rocco, P R
Format Journal Article
LanguageEnglish
Published New York American Thoracic Society 01.01.2017
Subjects
Cell adhesion & migration
Respiratory distress syndrome
Respiratory therapy
Rodents
Ventilators
Online AccessGet full text

Cover

More Information
Summary:In patients with acute respiratory distress syndrome (ARDS), improper mechanical ventilation settings can cause a secondary ventilator-induced lung injury (VILI). Amphiregulin (p=0.04) and vascular cell adhesion molecule (VCAM)-1 (p=0.04) mRNA expression was higher in VCV than NV, with no significant differences between P-APRV and VCV.
ISSN:1073-449X
1535-4970