C73 NEW MECHANISMS AND THERAPIES IN COPD: Adenine Nucleotide Translocase And Actin Interacting Protein-1 As New Targets In The Protection Of Airway Epithelial Cells Against Smoking-Related Disease And COPD

Corresponding author's email: cklimen1@jhmi.edu Rationale: Chronic obstructive pulmonary disease (COPD), the 3 leading cause of death in the US, is primarily due to cigarette smoke (CS) exposure. Conclusions: Combining the benefits of two model systems, human lung epithelium and Dictyostelium,...

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Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 195
Main Authors Kliment, C R, Nguyen, J, Wyatt, T A, Bailey, K L, Claypool, S M, Shapiro, S D, Sidhaye, V K, Robinson, D N
Format Journal Article
LanguageEnglish
Published New York American Thoracic Society 01.01.2017
Subjects
Chronic obstructive pulmonary disease
Disease
Gene expression
Hydration
Proteins
United States > US
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Summary:Corresponding author's email: cklimen1@jhmi.edu Rationale: Chronic obstructive pulmonary disease (COPD), the 3 leading cause of death in the US, is primarily due to cigarette smoke (CS) exposure. Conclusions: Combining the benefits of two model systems, human lung epithelium and Dictyostelium, provides a powerful approach for discovering new COPD biology while potentiating novel strategies for developing innovative COPD therapies.
ISSN:1073-449X
1535-4970