C67 SUPPURATIVE LUNG DISEASES IN CHILDREN: Differential Inflammatory Response During Acute Rsv Infection In Adult And Pediatric Mice

RSV is also an important cause of morbidity and mortality in the elderly population and is responsible for an annual average of 15 hospitalizations and 17 deaths per 1,000 nursing home residents. The aim of this study is to characterize the effects of RSV infection in pediatric and adult mice and de...

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Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 195
Main Authors Brady, V, Sharma, L, Liu, W, Dela Cruz, C S
Format Journal Article
LanguageEnglish
Published New York American Thoracic Society 01.01.2017
Subjects
Gene expression
Infections
Neutrophils
Older people
Pediatrics
Respiratory syncytial virus
Rodents
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Summary:RSV is also an important cause of morbidity and mortality in the elderly population and is responsible for an annual average of 15 hospitalizations and 17 deaths per 1,000 nursing home residents. The aim of this study is to characterize the effects of RSV infection in pediatric and adult mice and determine differences in the hosts' immune response to the virus that may lead to various degrees of illness severity.
ISSN:1073-449X
1535-4970