The influence of Matrix Metalloproteinase-9 upon the course of psoriasis in patients suffering from liver affections
The aim of our research has been the study of changes in the MMP-9 content in the blood of the patients suffering from psoriasis taking into account liver affection. Materials and Methods: It has been examined 128 patients suffering from uncomplicated plaque-like psoriasis of moderate degree of seve...
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Published in | The pharma innovation Vol. 2; no. 11, Part A; p. 38 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
New Delhi
The Pharma Innovation
01.01.2014
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Subjects | |
Online Access | Get full text |
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Summary: | The aim of our research has been the study of changes in the MMP-9 content in the blood of the patients suffering from psoriasis taking into account liver affection. Materials and Methods: It has been examined 128 patients suffering from uncomplicated plaque-like psoriasis of moderate degree of severity. Liver functional state has been evaluated according to the results of ultrasound and biochemical investigations. MMP-9 content in blood serum of the patients has been assessed by means of immunoferment analysis. Results: The increase of MMP-9 in the blood of patients was detected. The effect of MMP-9 for psoriasis in the direct correlation between these indices and index PASI was showed. (r = +0.43; p<0.05) Conclusion: The relation between MMP-9 in the blood of patients with psoriasis of moderate severity with disorder of the functional liver state was ascertained, that indicating for their combined participation in the immunopathogenesis of comorbid disorders. |
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ISSN: | 2277-7695 |