ANTIOXIDANT AND ANTICANCER ACTIVITIES OF Phyllanthus reteculatus
Medicinal plants contain physiologically active principles that over the years have been exploited in traditional medicine for the treatment of various ailments. The methanolic extract of Phyllanthus reteculatus was tested in-vitro as antioxidant and anticancer agent as well as for its phenolic and...
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Published in | Pharmacie Globale : International Journal of Comprehensive Pharmacy Vol. 7; no. 2; p. 1 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Roorkee
Pharmacie Globale
01.04.2016
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Subjects | |
Online Access | Get full text |
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Summary: | Medicinal plants contain physiologically active principles that over the years have been exploited in traditional medicine for the treatment of various ailments. The methanolic extract of Phyllanthus reteculatus was tested in-vitro as antioxidant and anticancer agent as well as for its phenolic and flavonoidal contents. The antioxidant activity of the plant extract was determined by 2, 2 diphenyl -1 -picrylhydrazyl (DPPH) assay while the trypan blue technique was used for the anticancer activity against Ehrlich Ascites Carcinoma Cells (EACC). The total phenolic and flavonoidal contents were estimated using colorimetric methods. The methanolic extract at a concentration of 13μg/ml possessed a considerable antioxidant activity against DPPH radical. Moreover, it caused 100% cytotoxic effect against EACC. Phyllanthus reteculatus extract was found to contain appreciable amounts of phenolic and flavonoidal compounds. It can be concluded that Phyllanthus reteculatus possesses sufficient in-vitro antioxidant and anticancer activities to warrant further detailed study of its pharmacology and phytochemistry. |
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ISSN: | 0976-8157 0976-8157 |