A Distinct Cardiomyopathy HCN4Syndrome Comprising Myocardial Noncompaction, Bradycardia, Mitral Valve Defects, and Aortic Dilation

Given the challenging analysis of mechanistic pathways leading to LVNC associated with previously identified mutations, this specific entity is expected to provide valuable novel insights into the complex pathomechanisms underlying LVNC that may include both hereditary and acquired components (1).

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Bibliographic Details
Published inJournal of the American College of Cardiology Vol. 69; no. 9; p. 1209
Main Authors Schweizer, Patrick A, Koenen, Michael, Katus, Hugo A, Thomas, Dierk
Format Journal Article
LanguageEnglish
Published New York Elsevier Limited 07.03.2017
Subjects
Cardiac arrhythmia
Cardiology
Cardiomyopathy
Mutation
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Summary:Given the challenging analysis of mechanistic pathways leading to LVNC associated with previously identified mutations, this specific entity is expected to provide valuable novel insights into the complex pathomechanisms underlying LVNC that may include both hereditary and acquired components (1).
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2016.10.085