Symptomatic Intracranial Atherosclerotic Disease

To provide an overview of the diagnosis, clinical presentation, and management of symptomatic intracranial atherosclerotic disease (ICAD). Review of the current literature in the context of a clinical case. ICAD is a common cause of ischemic strokes or transient ischemic attacks (TIAs), especially a...

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Bibliographic Details
Published inJournal of clinical outcomes management Vol. 23; no. 6; p. 1
Main Authors Winningham, Melanie J, Nahab, Fadi
Format Journal Article
LanguageEnglish
Published Wayne Turner White Communications Inc 01.06.2016
Subjects
Atherosclerosis
Disease management
Literature reviews
Medical diagnosis
Stroke
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Summary:To provide an overview of the diagnosis, clinical presentation, and management of symptomatic intracranial atherosclerotic disease (ICAD). Review of the current literature in the context of a clinical case. ICAD is a common cause of ischemic strokes or transient ischemic attacks (TIAs), especially among Asian, black, and Hispanic patients. ICAD can be identified with noninvasive arterial imaging such as CT angiography, MR angiography, or transcranial Doppler ultrasound of the head when evaluating for the cause of an ischemic stroke or TIA. Aggressive medical management with dual antiplatelet therapy and lifestyle and risk factor modification has emerged as effective first-line therapy. In patients who have recurrent ischemic symptoms while on aggressive medical management, endovascular treatment can be considered. When symptomatic ICAD is identified early, aggressive medical management is effective in reducing the risk of recurrent ischemic events in this patient population.
ISSN:1079-6533
1938-1336