Authors' response

The serum, soft tissue and peritoneal fluid concentrations of both amoxicillin and clavulanate, achieved following the administration of 1g and 200 mg, respectively, are in excess of the minimum inhibitory concentrations of key potential pathogens, and therefore a larger dose is considered unnecessa...

Full description

Saved in:
Bibliographic Details
Published inGut Vol. 59; no. 9; p. 1300
Main Authors Sandoe, Jonathan A T, Allison, Miles C, Elliott, Thomas S J
Format Journal Article
LanguageEnglish
Published London BMJ Publishing Group LTD 01.09.2010
Online AccessGet full text

Cover

More Information
Summary:The serum, soft tissue and peritoneal fluid concentrations of both amoxicillin and clavulanate, achieved following the administration of 1g and 200 mg, respectively, are in excess of the minimum inhibitory concentrations of key potential pathogens, and therefore a larger dose is considered unnecessary. Since the recommendations are pragmatic, we entirely support the need for active surveillance of infection and further appropriate clinical trials.
ISSN:0017-5749
1468-3288
DOI:10.1136/gut.2010.220806