Structure and Morphology of Nanocrystalline Calcifications in Thyroid

• Published in: Journal of Nano- and Electronic Physics Vol. 8; no. 1; p. 1031-1
• Main Authors: Danilchenko, S N, Stanislavov, A S, Kuznetsov, V N, Kochenko, A V, Kalinichenko, T G, Rieznik, A V, Starikov, V V, Moskalenko, R A, Romaniuk, A M
• Format: Journal Article
• Language: Russian; Ukrainian
• Published: Sumy Ukraine Sumy State University, Journal of Nano - and Electronic Physics 01.01.2016
• ISSN: 2077-6772; 2306-4277

The paper presents the results of study on morphology, structure, elemental and phase composition of the calcified fragments from pathological formations of the thyroid gland. The X-ray diffraction and infrared spectroscopy revealed that all investigated pathological calcifications are represented by a defective carbonate substituted calcium apatite Ca10(PO4)6(OH)2. The use of transmission electron microscopy in combination with electron microdiffraction is shown to reveal some structural and morphological features of crystals of thyroid apatite, which are not detectable by other methods. Therefore, the local morphological and structural analysis of a mineral component of the deposits can be implemented both in one clinical case, and in wide variety of cases, if a delicate preparation at anatomical studies and sample preparation procedure will be applied.