Incidence of type 2 diabetes and number of events attributable to abdominal obesity in China: A cohort study; 2è°[beta]èz

• Published in: Journal of diabetes Vol. 8; no. 2; p. 190
• Main Authors: Xue, Haifeng, Wang, Chao, Li, Ying, Chen, Jichun, Yu, Ling, Liu, Xiaoqing, Li, Jianxin, Cao, Jie, Deng, Ying, Guo, Dongshuang, Yang, Xueli, Huang, Jianfeng, Gu, Dongfeng
• Format: Journal Article
• Language: English
• Published: Hoboken John Wiley & Sons, Inc 01.03.2016
• Subjects: Abdomen; Confidence intervals; Diabetes; Obesity; Women
• ISSN: 1753-0393; 1753-0407
• DOI: 10.1111/1753-0407.12273

Background The aim of the present study was to estimate the incidence of type 2 diabetes (T2D) and the number of diabetes events attributable to abdominal obesity in China. Methods A cohort study was conducted in a sample of 24996 Chinese adults aged 35-74 years, with 19.9% of subjects lost to follow-up. Waist circumference (WC) was measured at baseline in 1998 and 2000-01, and abdominal obesity was defined as WC≥90cm in men and ≥80cm in women. Information on incident diabetes was collected during follow-up in 2007-08. We estimated the number of T2D events attributed to abdominal obesity using confounder-adjusted population-attributable risk, incidence of diabetes, and the population size of China in 2010. Results After a mean follow-up of 8.0 years, the age-standardized incidence of T2D was 9.6 and 9.2 per 1000 person-years in men and women, respectively. Abdominal obesity accounted for 28.1% (95% confidence interval [CI] 14.8%, 40.5%) of incident diabetes among men and 41.2% (95% CI 28.3%, 52.6%) among women using the diagnostic criteria of abdominal obesity recommended by the International Diabetes Federation. We estimated that, in 2010, 2.4 (95% CI 1.5, 3.2) million diabetes events were attributable to abdominal obesity: 1.0 (95% CI 0.5, 1.4) million in men and 1.4 (95% CI 1.0, 1.8) million in women. Conclusions Abdominal obesity is a major risk factor for T2D. Strengthening programs and initiatives for preventing and controlling obesity focusing on lifestyle changes should be a priority in the national strategy to reduce diabetes burden in China. 2è- 2499635-74è¿>,19982000è°,2007-2008ä¾<,19.9%è-:≥ 90 cm,≥ 80 cmè°ç¾¤å½'2010,è- 8.0,35-74é¾,,29.6/1000-9.2/1000-è-,è-28.1%(95% CI:14.8%,40.5%)41.2%(95% CI:28.3%,52.6%)2010è-240(95% CI:150,320)ä¾<,100(95% CI:50,140),140(95% CI:100,180) è-2,è-,è½»