Dysfunction of Rice Mitochondrial Membrane Induced by Yb^sup 3

Ytterbium (Yb), a widely used rare earth element, is treated as highly toxic to human being and adverseness to plant. Mitochondria play a significant role in plant growth and development, and are proposed as a potential target for ytterbium toxicity. In this paper, the biological effect of Yb^sup 3+...

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Bibliographic Details
Published inThe Journal of membrane biology Vol. 248; no. 6; p. 1159
Main Authors Gao, Jia-ling, Wu, Man, Liu, Wen, Feng, Zhi-jiang, Zhang, Ye-zhong, Jiang, Feng-lei, Liu, Yi, Dai, Jie
Format Journal Article
LanguageEnglish
Published Heidelberg Springer Nature B.V 01.12.2015
Subjects
Flowers & plants
Membranes
Mitochondria
Rice
Toxicity
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Summary:Ytterbium (Yb), a widely used rare earth element, is treated as highly toxic to human being and adverseness to plant. Mitochondria play a significant role in plant growth and development, and are proposed as a potential target for ytterbium toxicity. In this paper, the biological effect of Yb^sup 3+^ on isolated rice mitochondria was investigated. We found that Yb^sup 3+^ with high concentrations (200 ~ 600 [mu]M) not only induced mitochondrial membrane permeability transition (mtMPT), but also disturbed the mitochondrial ultrastructure. Moreover, Yb^sup 3+^ caused the respiratory chain damage, ROS formation, membrane potential decrease, and mitochondrial complex II activity reverse. The results above suggested that Yb^sup 3+^ with high concentrations could induce mitochondrial membrane dysfunction. These findings will support some valuable information to the safe application of Yb-based agents.
ISSN:0022-2631
1432-1424
DOI:10.1007/s00232-015-9833-6