GW26-e1336 Myocardial Protection by MiR-126 Against Ischemia/Reperfusion Injury Through Suppression of GSK-3[beta]
Stretch or enforced expression of miR-126 significantly decreased I/R-induced myocardial infarct size by 42% and attenuated I/R-induced myocardial apoptosis, together with down-regulation of glycogen synthase kinase 3 beta (GSK-3β) (p<0.05).
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Published in | Journal of the American College of Cardiology Vol. 66; no. 16; p. C40 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
Elsevier Limited
20.10.2015
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Subjects | |
Online Access | Get full text |
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Summary: | Stretch or enforced expression of miR-126 significantly decreased I/R-induced myocardial infarct size by 42% and attenuated I/R-induced myocardial apoptosis, together with down-regulation of glycogen synthase kinase 3 beta (GSK-3β) (p<0.05). |
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ISSN: | 0735-1097 1558-3597 |
DOI: | 10.1016/j.jacc.2015.06.1178 |