Metal-Free Oxidative CC Bond Formation through CH Bond Functionalization

The formation of CC bonds embodies the core of organic chemistry because of its fundamental application in generation of molecular diversity and complexity. CC bond-forming reactions are well-known challenges. To achieve this goal through direct functionalization of CH bonds in both of the coupling...

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Bibliographic Details
Published inChemistry : a European journal Vol. 21; no. 42; p. 14678
Main Authors Narayan, Rishikesh, Matcha, Kiran, Antonchick, Andrey P
Format Journal Article
LanguageEnglish
Published Weinheim Wiley Subscription Services, Inc 12.10.2015
Subjects
Chemistry
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Summary:The formation of CC bonds embodies the core of organic chemistry because of its fundamental application in generation of molecular diversity and complexity. CC bond-forming reactions are well-known challenges. To achieve this goal through direct functionalization of CH bonds in both of the coupling partners represents the state-of-the-art in organic synthesis. Oxidative CC bond formation obviates the need for prefunctionalization of both substrates. This Minireview is dedicated to the field of CC bond-forming reactions through direct CH bond functionalization under completely metal-free oxidative conditions. Selected important developments in this area have been summarized with representative examples and discussions on their reaction mechanisms.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201502005