Silica-Supported Tungstic Acid Catalyzed Synthesis and Antioxidant Activity of [alpha]-Hydroxyphosphonates

A green and efficient method has been accomplished for the synthesis of α-hydroxyphosphonates using silica-supported tungstic acid (STA) as a heterogeneous catalyst under solvent-free conditions at ambient temperature. The compounds obtained were characterized by spectral and analytical studies and...

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Published inPhosphorus, sulfur, and silicon and the related elements Vol. 190; no. 9; p. 1479
Main Authors Santhisudha, S, Sreelakshmi, P, Jayaprakash, S. H, Vijaya Kumar, B, Suresh Reddy, C
Format Journal Article
LanguageEnglish
Published Abingdon Taylor & Francis Ltd 01.09.2015
Subjects
Acids
Antioxidants
Free radicals
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Summary:A green and efficient method has been accomplished for the synthesis of α-hydroxyphosphonates using silica-supported tungstic acid (STA) as a heterogeneous catalyst under solvent-free conditions at ambient temperature. The compounds obtained were characterized by spectral and analytical studies and screened in vitro for the antioxidant activity by four methods viz., DPPH free radical scavenging assay, hydrogen peroxide scavenging assay, NO method, FRAP method. The results indicated that the title compounds are potential antioxidants and are comparable to the antioxidant property of the standard ascorbic acid.
ISSN:1042-6507
1563-5325
DOI:10.1080/10426507.2014.991825