EFFECT OF STRESS DOSE OF EPINEPHRINE ON THE HISTOLOGY OF LIVER IN MALE MICE

Aim of the current study was to evaluate the effect of daily exposure to stress on the liver histology in male mice, and relation with the duration of exposure to stress. Also to evaluate whether vitamin B-complex can reduce the effect of stress. The results of this study demonstrated that receiving...

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Published inPharmacie Globale : International Journal of Comprehensive Pharmacy Vol. 6; no. 2; p. 1
Main Authors Abdullah, Rand Abdulateef, Jarjees, Mohammed Taib T, Al-Youzbaki, Wahda Basheer
Format Journal Article
LanguageEnglish
Published Roorkee Pharmacie Globale 01.04.2015
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Summary:Aim of the current study was to evaluate the effect of daily exposure to stress on the liver histology in male mice, and relation with the duration of exposure to stress. Also to evaluate whether vitamin B-complex can reduce the effect of stress. The results of this study demonstrated that receiving a stress dose of epinephrine causing a significantly lower mean liver weights of group G2 and G3 of the studied mice in comparison with those of the other studied groups, but a non significant differences between these two groups. The histological study of the liver sections of group G2 mice revealed that most of hepatocytes looked normal and few hepatocytes showed ballooning degeneration. In group G3 the lobular architecture was disturbed with disarray of hepatocytes. Some hepatocytes showed severe ballooning degeneration, and necrosis. Some hepatocytes suffer from micro vesicular steatosis with destructions of bile ducts and stasis.
ISSN:0976-8157
0976-8157