ChemInform Abstract: [gamma]-Aminoalcohol Rearrangement Applied to Pentahydroxylated Azepanes Provides Pyrrolidines Epimeric to HomoDMDP

A short sequence is described for the conversion of azepanes (I) and (V) into pyrrolidines (IV) and (VIII), which are epimeric to [alpha]-glucosidase inhibitor homoDMDP.

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Bibliographic Details
Published inChemInform Vol. 46; no. 28
Main Authors Jagadeesh, Y, Tran, A T, Luo, B, Auberger, N, Desire, J, Nakagawa, S, Kato, A, Zhang, Y, Sollogoub, M, Bleriot, Y
Format Journal Article
LanguageEnglish
Published Frankfurt Wiley Subscription Services, Inc 01.07.2015
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Summary:A short sequence is described for the conversion of azepanes (I) and (V) into pyrrolidines (IV) and (VIII), which are epimeric to [alpha]-glucosidase inhibitor homoDMDP.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201528140