Co-occurrence of Point Mutations in the Voltage-Gated Sodium Channel of Pyrethroid-Resistant Aedes aegypti Populations in Myanmar e3032

[33] concluded that prolonged use of pyrethroids for malaria control may be one of the causative factors of pyrethroid resistance in Aedes aegypti in Vietnam. Since the abandonment of DDT sprays in Vietnam in 1995, a large number of photostable pyrethroids (λ-cyhalothrin, α-cypermethrin, deltameth...

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Bibliographic Details
Published inPLoS neglected tropical diseases Vol. 8; no. 7
Main Authors Kawada, Hitoshi, Oo, Sai ZawMin, Thaung, Sein, Kawashima, Emiko, Maung, Yan NaungMaung, Thu, Hlaing Myat, Thant, Kyaw Zin, Minakawa, Noboru
Format Journal Article
LanguageEnglish
Published San Francisco Public Library of Science 01.07.2014
Subjects
Genetic engineering
Insecticides
Malaria
Mosquitoes
Mutation
Tropical diseases
Myanmar (Burma)
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Summary:[33] concluded that prolonged use of pyrethroids for malaria control may be one of the causative factors of pyrethroid resistance in Aedes aegypti in Vietnam. Since the abandonment of DDT sprays in Vietnam in 1995, a large number of photostable pyrethroids (λ-cyhalothrin, α-cypermethrin, deltamethrin, and permethrin) have been used to treat the interiors of houses as a residual spray, and to manufacture pyrethroid-impregnated bed nets for malaria control [1], [34]-[36]. Transitional life-prolonging measures for conventional 1st generation pyrethroids that belong to the photo-unstable knockdown agent groups and are used as "spatial repellents" [42], rotational use of plural insecticides with different mode of actions, and basic biochemical and genetic research to support the above strategies, are crucial to the effective management of insecticide resistance.
ISSN:1935-2727
1935-2735
DOI:10.1371/journal.pntd.0003032