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Traditional Chinese herbal medications have drawn growing attention for research worldwide. This article investigated how to efficiently identify effective compounds in a herbal medicine via chromatographic fingerprints, which could shed light on the efficacy of the medicine. The article adopted spa...

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Bibliographic Details
Published inJournal of the American Statistical Association Vol. 109; no. 508; p. 1350
Main Authors Chen, Huaihou, Zeng, Donglin
Format Journal Article
LanguageEnglish
Published Alexandria Taylor & Francis Ltd 01.12.2014
Subjects
Chinese medicine
Chromatography
Herbal medicine
Mathematical models
Phytochemicals
Statistics
China
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Summary:Traditional Chinese herbal medications have drawn growing attention for research worldwide. This article investigated how to efficiently identify effective compounds in a herbal medicine via chromatographic fingerprints, which could shed light on the efficacy of the medicine. The article adopted sparse but flexible semiparametric nonlinear models for both the fingerprint shape and the warping functions.
ISSN:0162-1459
1537-274X