A keratitis rat model for evaluation of anti-Acanthamoeba polyphagiaagents

The highest ratio of abscesses in five-week-old Sprague-Dawley male rats was obtained with a combination of intrastromal injection of 104 trophozoites with a regimen of subconjunctival injection of 0.28 mg/week betamethasone.

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Bibliographic Details
Published inAmerican journal of ophthalmology Vol. 142; no. 6; p. 1095
Main Authors Vasseneix, C, Gargala, G, Francois, A, Hellot, MF, Duclos, C, Muraine, M, Benichou, J, Ballet, JJ, Brasseur, G, Favennec, L
Format Journal Article
LanguageEnglish
Published Chicago Elsevier Limited 01.12.2006
Subjects
Rodents
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Summary:The highest ratio of abscesses in five-week-old Sprague-Dawley male rats was obtained with a combination of intrastromal injection of 104 trophozoites with a regimen of subconjunctival injection of 0.28 mg/week betamethasone.
ISSN:0002-9394
1879-1891
DOI:10.1016/j.ajo.2006.10.011