Schistosoma japonicumcalcium-binding tegumental protein SjTP22.4 immunization confers praziquantel schistosomulumicide and antifecundity effect in mice

Highlights * We cloned and characterized TP22.4, a novel tegumental protein inS. japonicum. * Circular dichroism measurement demonstrates SjTP22.4 has Ca2+binding ability. * TP22.4 immunization showed a decrease in liver pathology in challenge experiment. * SjTP22.4 combined with praziquantel showed...

Full description

Saved in:
Bibliographic Details
Published inVaccine Vol. 30; no. 34; p. 5141
Main Authors Zhang, Zhaoping, Xu, Hongxu, Gan, Wenjia, Zeng, Suxiang, Hu, Xuchu
Format Journal Article
LanguageEnglish
Published Kidlington Elsevier Limited 20.07.2012
Subjects
Antigens
Bioinformatics
Cattle
Cloning
Eggs
Immunization
Immunology
Infections
Liver
Molecular weight
Pathology
Proteins
China
Africa
Online AccessGet full text

Cover

Abstract Highlights * We cloned and characterized TP22.4, a novel tegumental protein inS. japonicum. * Circular dichroism measurement demonstrates SjTP22.4 has Ca2+binding ability. * TP22.4 immunization showed a decrease in liver pathology in challenge experiment. * SjTP22.4 combined with praziquantel showed more significant protection. * SjTP22.4 with PZQ is of value in killing schistosomulum.
AbstractList Highlights * We cloned and characterized TP22.4, a novel tegumental protein inS. japonicum. * Circular dichroism measurement demonstrates SjTP22.4 has Ca2+binding ability. * TP22.4 immunization showed a decrease in liver pathology in challenge experiment. * SjTP22.4 combined with praziquantel showed more significant protection. * SjTP22.4 with PZQ is of value in killing schistosomulum.
Author Xu, Hongxu
Gan, Wenjia
Hu, Xuchu
Zeng, Suxiang
Zhang, Zhaoping
Author_xml – sequence: 1
  givenname: Zhaoping
  surname: Zhang
  fullname: Zhang, Zhaoping
– sequence: 2
  givenname: Hongxu
  surname: Xu
  fullname: Xu, Hongxu
– sequence: 3
  givenname: Wenjia
  surname: Gan
  fullname: Gan, Wenjia
– sequence: 4
  givenname: Suxiang
  surname: Zeng
  fullname: Zeng, Suxiang
– sequence: 5
  givenname: Xuchu
  surname: Hu
  fullname: Hu, Xuchu
BookMark eNqNjcFKAzEQhoO04Nb6CELA865JdrNdz6J4FNqDtxKzs3WWzaTdJIJ9EV_XHMRzYX5mYD7-b8UW5AkYu5OikkK2D2P1ZaxFgkoJqSqh87RXrJDdpi6Vlt2CFUK1TdlI8X7NViGMQghdy8eC_WztJ4bog3eGj-boCW1y1kwWkys_kHqkA49wSA4omokfZx8BiW_H3ZtSVcPRuUR4NhE9cetpgDlkypzxlAxFmHj4V6QpObTYAzfU50QcwKbsiN8chnxHnqszAmu2HMwU4PZv37D7l-fd02uZ_acEIe5Hn2bKr71sle60Fpu2voz6BS34Zfk
ContentType Journal Article
Copyright Copyright Elsevier Limited Jul 20, 2012
Copyright_xml – notice: Copyright Elsevier Limited Jul 20, 2012
DBID 3V.
7QL
7RV
7T2
7T5
7U9
7X7
7XB
88C
88E
8AO
8C1
8FE
8FH
8FI
8FJ
8FK
8G5
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
C1K
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
GUQSH
H94
HCIFZ
K9-
K9.
KB0
LK8
M0R
M0S
M0T
M1P
M2O
M7N
M7P
MBDVC
NAPCQ
PQEST
PQQKQ
PQUKI
Q9U
DOI 10.1016/j.vaccine.2012.05.056
DatabaseName ProQuest Central (Corporate)
Bacteriology Abstracts (Microbiology B)
ProQuest Nursing & Allied Health Database
Health and Safety Science Abstracts (Full archive)
Immunology Abstracts
Virology and AIDS Abstracts
Health & Medical Collection (Proquest)
ProQuest Central (purchase pre-March 2016)
Healthcare Administration Database (Alumni)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
ProQuest Public Health Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
Research Library (Alumni Edition)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
AUTh Library subscriptions: ProQuest Central
ProQuest Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
Research Library Prep
AIDS and Cancer Research Abstracts
SciTech Premium Collection (Proquest) (PQ_SDU_P3)
Consumer Health Database
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
Biological Sciences
Family Health Database (Proquest)
Health & Medical Collection (Alumni Edition)
Health Management Database (Proquest)
PML(ProQuest Medical Library)
ProQuest Research Library
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Research Library (Corporate)
Nursing & Allied Health Premium
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central Basic
DatabaseTitle Research Library Prep
ProQuest Central Student
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
Research Library (Alumni Edition)
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Family Health (Alumni Edition)
Environmental Sciences and Pollution Management
ProQuest Central
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Collection
AIDS and Cancer Research Abstracts
ProQuest Research Library
Health & Safety Science Abstracts
ProQuest Medical Library (Alumni)
ProQuest Public Health
Virology and AIDS Abstracts
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest Family Health
ProQuest One Academic Eastern Edition
ProQuest Health Management
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
ProQuest Hospital Collection (Alumni)
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest Health Management (Alumni Edition)
Immunology Abstracts
ProQuest Nursing & Allied Health Source (Alumni)
ProQuest One Academic
ProQuest Central (Alumni)
DatabaseTitleList Research Library Prep
Database_xml – sequence: 1
  dbid: BENPR
  name: AUTh Library subscriptions: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Veterinary Medicine
Biology
Pharmacy, Therapeutics, & Pharmacology
EISSN 1873-2518
ExternalDocumentID 3500149111
GeographicLocations China
Africa
GeographicLocations_xml – name: China
– name: Africa
GroupedDBID ---
--K
--M
.1-
.FO
.~1
0R~
123
1B1
1P~
1RT
1~.
1~5
3V.
4.4
457
4G.
53G
5RE
5VS
7-5
71M
7QL
7RV
7T2
7T5
7U9
7X7
7XB
88E
8AO
8C1
8FE
8FH
8FI
8FJ
8FK
8G5
8P~
9JM
AAAJQ
AABNK
AACTN
AAEDT
AAEDW
AAHBH
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AARKO
AAXKI
AAXUO
ABBQC
ABFNM
ABFRF
ABJNI
ABKYH
ABMAC
ABMZM
ABRWV
ABUWG
ABXDB
ACDAQ
ACGFO
ACGFS
ACIUM
ACPRK
ACRLP
ADBBV
ADEZE
ADFRT
ADMUD
AEBSH
AEFWE
AEKER
AENEX
AEVXI
AEXOQ
AFCTW
AFKRA
AFKWA
AFRAH
AFRHN
AFTJW
AFXIZ
AGEKW
AGGSO
AGUBO
AGYEJ
AHMBA
AIEXJ
AIKHN
AITUG
AJOXV
AJRQY
AJUYK
AKRWK
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ANZVX
AQUVI
AXJTR
AZQEC
BBNVY
BENPR
BHPHI
BKEYQ
BKNYI
BKOJK
BLXMC
BNPGV
BPHCQ
BVXVI
C1K
CCPQU
CJTIS
CNWQP
CS3
DWQXO
EBS
EFJIC
EJD
EO8
EO9
EP2
EP3
F5P
FDB
FIRID
FNPLU
FYGXN
FYUFA
G-Q
GBLVA
GNUQQ
GUQSH
H94
HCIFZ
HZ~
IHE
J1W
K9-
K9.
KOM
L7B
LK8
LUGTX
LW9
M0R
M0T
M1P
M29
M2O
M41
M7N
M7P
MBDVC
MO0
N9A
NAPCQ
O-L
O9-
O9~
OAUVE
OK0
OZT
P-8
P-9
P2P
PC.
PQEST
PQQKQ
PQUKI
PROAC
PSQYO
Q38
Q9U
RIG
ROL
RPZ
SAB
SCC
SDF
SDG
SDP
SES
SNL
SPCBC
SSH
SSI
SSZ
T5K
UV1
WH7
WOW
Z5R
~G-
ID FETCH-proquest_journals_16258550763
IEDL.DBID 8C1
ISSN 0264-410X
IngestDate Thu Oct 10 21:03:02 EDT 2024
IsPeerReviewed true
IsScholarly true
Issue 34
Language English
LinkModel DirectLink
MergedId FETCHMERGED-proquest_journals_16258550763
PQID 1625855076
PQPubID 105530
ParticipantIDs proquest_journals_1625855076
PublicationCentury 2000
PublicationDate 20120720
PublicationDateYYYYMMDD 2012-07-20
PublicationDate_xml – month: 07
  year: 2012
  text: 20120720
  day: 20
PublicationDecade 2010
PublicationPlace Kidlington
PublicationPlace_xml – name: Kidlington
PublicationTitle Vaccine
PublicationYear 2012
Publisher Elsevier Limited
Publisher_xml – name: Elsevier Limited
SSID ssj0005319
Score 4.146697
Snippet Highlights * We cloned and characterized TP22.4, a novel tegumental protein inS. japonicum. * Circular dichroism measurement demonstrates SjTP22.4 has...
SourceID proquest
SourceType Aggregation Database
StartPage 5141
SubjectTerms Antigens
Bioinformatics
Cattle
Cloning
Eggs
Immunization
Immunology
Infections
Liver
Molecular weight
Pathology
Proteins
Title Schistosoma japonicumcalcium-binding tegumental protein SjTP22.4 immunization confers praziquantel schistosomulumicide and antifecundity effect in mice
URI https://www.proquest.com/docview/1625855076
Volume 30
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8JQFD-kUvQStYo-TC4UPjl13_MpShQJlJEWe5PrdheTnNq2wP6R_t3OvZstCHzY0-7H2Lnc8_U7vwNwF5g-Q4fNli3N0tFBYZ7c6QRUDnTVs-1OW6eiHdBwZA5e9CfXcPOAW5zDKrd3orio_aXHY-QtBQ11Qb5l3q_WMu8axbOreQuNElQU1HMc0md3_0A8NNHYA90M_Ayl7RYVPK1585N6PHXN0V2qIO80zH_3sVAy_WM4yq1D8pCJ8wT2WCTBftYvciPBwTDPhEtQdzLO6U2DTIoSqrhB6sQp2KhxjvTKAS-i6pZsp5_C99gTTMPxckHJnK44QW66QHl5Ybrg3jJXaSRhb2lG_k8En0MYkfF84qhqUyehKCzJijiJJ-oGYxxFv8J1yqX1TuLfLXiEETf2GaGRj08SBsxLebJ8QzJACcGlcQg7g9t-b9IdyNs_NM0PezwtRKOdQzlaRuwCCGVMN5TA8g06Qx-SohZkgaJZQdtmaLXNLqG6a6Wr3a-v4ZDLjQdZ1XYVyslHym7QOkhmNShZrlUTB6EGlcfeyHn-AfA7xdg
link.rule.ids 315,783,787,12068,12235,21400,27936,27937,31731,33278,33756,43322,43591,43817,74073,74342,74630
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1JT8JAFH5RjMvFaNW4oE6i4USh-3IyhkhQgZCAhhsZ2qkpkQK2NcE_4t_1zbRYExMOPXWWZt707e97ALeB5TM02BzZ1m0DDRTmya4bUDkwNM9xXMWgoh1Qp2u1XoynoTnMHW5xnla54omCUfszj_vI6yoq6gJ8y7qbL2TeNYpHV_MWGpuwhWLf5T-m0_iT4qGLxh5oZuBnqMqwqOCpT2qf1OOha57dpQnwTtP6x4-FkGkewH6uHZL7jJyHsMEiCbazfpFLCXY6eSRcgkovw5xeVsmgKKGKq6RCegUaNc6RXnnCi6i6JavpR_Dd9wTScDybUjKhcw6Qm06RXl6YTrm1zEUaSdhbmoH_E4HnEEakPxn0NK1mkFAUlmRFnMQTdYMxjqJf4SLl1Hon8e8W3MOIG_uM0MjHJwkD5qU8WL4kWUIJwaVxCDuGm-bDoNGSVyc0yi97PCpIo59AKZpF7BQIZcww1cD2TTpGG5KiFGSBqtuB4jDU2sZnUF630vn619ew2xp02qP2Y_f5AvY4DbnDVVPKUEo-UnaJmkIyvhLX4QeQIcZK
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1JT8JAFH5RiMSL0apxQZ1Ew4lCN9pyMi4QXCCNoOFGhnZqSqSAbU3wj_h3fTMt9mDCoafO0vRN5m3f-x7AlW96DB02W7Z0y0AHhblys-lT2Tc017abikFFO6Buz-y8Go_DxjDDP0UZrHJ1J4qL2pu5PEZeV9FQF-RbZt3PYBHOfft6vpB5Bymeac3aaWxC0TJMXSlA8bbVc15ywIcu2nyg04EfpSrDvJ6nPql9UZcnsjnWSxNUng3z3-0sVE57F3YyW5HcpMLdgw0WSrCVdo9cSlDqZnlxCSpOykC9rJJBXlAVVUmFODk3Nc6R3jj8RdTgktX0ffjpu4J3OJpNKZnQOafLTaYoPTdIptx35gqOxOw9SVsBEMHuEISkPxk4mlYzSCDKTNKSTuKKKsIIR9HvYJFw2X2Q6G8LHm_EjT1GaOjhEwc-cxOeOl-SFF5CcGkcwg7gst0a3HXk1R8aZUc_GuWC0g-hEM5CdgSEMmY0VN_yGnSMHiVFnch8Vbd8xWZow42PobxupZP1ry-ghGdh9PzQezqFbS5CHn3VlDIU4s-EnaHZEI_Ps_PwC6xYzBM
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Schistosoma+japonicumcalcium-binding+tegumental+protein+SjTP22.4+immunization+confers+praziquantel+schistosomulumicide+and+antifecundity+effect+in+mice&rft.jtitle=Vaccine&rft.au=Zhang%2C+Zhaoping&rft.au=Xu%2C+Hongxu&rft.au=Gan%2C+Wenjia&rft.au=Zeng%2C+Suxiang&rft.date=2012-07-20&rft.pub=Elsevier+Limited&rft.issn=0264-410X&rft.eissn=1873-2518&rft.volume=30&rft.issue=34&rft.spage=5141&rft_id=info:doi/10.1016%2Fj.vaccine.2012.05.056&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=3500149111
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0264-410X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0264-410X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0264-410X&client=summon