Effects of MR-invisible objects and object attenuation on PET quantification in small animal PET/MR imaging

Conference Title: 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC) Conference Start Date: 2013, Oct. 27 Conference End Date: 2013, Nov. 2 Conference Location: Seoul, Korea (South) PET Attenuation Correction (AC) in small animal imaging is generally performed via tran...

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Published inThe Institute of Electrical and Electronics Engineers, Inc. (IEEE) Conference Proceedings p. 1
Main Authors Bezrukov, Ilja, Wehrl, Hans F, Liu, Chih-Chieh, Hossain, Mosaddek, Mantlik, Frederic, Pichler, Bernd J
Format Conference Proceeding
LanguageEnglish
Published Piscataway The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 01.10.2013
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Summary:Conference Title: 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC) Conference Start Date: 2013, Oct. 27 Conference End Date: 2013, Nov. 2 Conference Location: Seoul, Korea (South) PET Attenuation Correction (AC) in small animal imaging is generally performed via transmission (TX) scans. In simultaneous PET/MR scanners, no transmission source is available, and MR-based AC (MRAC) or AC from emission data is necessary. However, MR-invisible objects such as the bed and the MR coils cannot be corrected from MR data. We quantified the effects of a Medres warming bed and a local brain coil on AC for small animal PET/MR imaging using a dedicated Inveon PET tomograph. Additionally, the effect of segmentation-based MRAC of rats in brain regions was evaluated using MR images separately acquired on a preclinical 7T MRI system. [PUBLICATION ABSTRACT]