Long-Term Outcomes of Bariatric Surgery in Obese Adults

• Published in: Journal of clinical outcomes management Vol. 21; no. 6; p. 2416
• Main Authors: Courcoulas, AP, Christian, NJ, Belle, SH
• Format: Journal Article
• Language: English
• Published: Wayne Turner White Communications Inc 01.06.2014
• Subjects: Body mass index; Diabetes; Gastrointestinal surgery; Hypertension; Obesity; United States > US
• ISSN: 1079-6533; 1938-1336

To identify the long-term outcomes of bariatric surgery in adults with severe obesity. Prospective longitudinal observational cohort study (the Longitudinal Assessment of Bariatric Surgery Consortium [LABS]). LABS was established to collect long-term data on safety and efficacy of bariatric surgeries. 2458 patients who underwent Roux-en-Y gastric bypass (RYGB) or laparoscopic adjustable gastric banding (LAGB) at 10 hospitals in 6 clinical centers in the United States. Participants were included if they had a body mass index (BMI) greater than 35 kg/m2 , were over the age of 18 years, and had not undergone prior bariatric surgeries. Participants were recruited between 2006 and 2009, and follow-up continued until September 2012. Data collection occurred at baseline prior to surgery and then at 6 months, 12 months, and annually until 3 years following surgery. 3-year change in weight and resolution of diabetes, hypertension, and dyslipidemia. Participants were between the ages of 18 and 78 years. The majority of participants were female (79%) and white (86%). Median BMI was 45.9 (interquartile range [IQR], 41.7-51.5). At baseline, 774 (33%) had diabetes, 1252 (63%) had dyslipidemia, and 1601 (68%) had hypertension. Three years after surgery, the LAGB group exhibited greater weight loss (median 41 kg vs. 20 kg). Participants experienced most of their total weight loss during the first year following surgery. As for the health parameters assessed, at 3 years 67.5% of RYGB patients and 28.6% of LAGB patients had at least partial diabetes remission, 61.9% of RYGB patients and 27.1% of LAGB patients had dyslipidemia remission, and 38.2% of RYGB patients and 17.4 % of LAGB patients had hypertension remission. Three years following bariatric surgery, participants with severe obesity exhibited significant weight loss. There was variability in the amount of weight loss and in resolution of diabetes, hypertension and dyslipidemia observed.