Water, Sanitation, and Hygiene (WASH): A Critical Component for Sustainable Soil-Transmitted Helminth and Schistosomiasis Control e2651

A second is that small sections of the population usually remain out of reach of chemotherapy programmes, subgroups that frequently have a disproportionately heavy burden of infection, thereby serving as a reservoir for reinfection. [...]longer-term effectiveness of chemotherapy in interrupting tran...

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Published inPLoS neglected tropical diseases Vol. 8; no. 4
Main Authors Campbell, Suzy J, Savage, Georgia B, Gray, Darren J, Atkinson, Jo-An M, Magalhães, Ricardo JSoares, Nery, Susana V, McCarthy, James S, Velleman, Yael, Wicken, James H, Traub, Rebecca J, Williams, Gail M, Andrews, Ross M, Clements, Archie CA
Format Journal Article
LanguageEnglish
Published San Francisco Public Library of Science 01.04.2014
Subjects
Chemotherapy
Colleges & universities
Councils
Disease
Drug resistance
Hygiene
Infections
Morbidity
Sanitation
School attendance
Tropical diseases
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Summary:A second is that small sections of the population usually remain out of reach of chemotherapy programmes, subgroups that frequently have a disproportionately heavy burden of infection, thereby serving as a reservoir for reinfection. [...]longer-term effectiveness of chemotherapy in interrupting transmission is dependent on maintenance of regular retreatment. Other issues that are not yet resolved with regards to chemotherapy include potential teratogenic effects of benzimidazole drugs and associations with eczema in children following maternal chemotherapy during pregnancy [24]. [...]whilst chemotherapy is necessary to rapidly reduce the burden and morbidity of helminth infections, we argue that by itself it is an unsustainable strategy for helminth control and for reaching control and elimination targets.
ISSN:1935-2727
1935-2735
DOI:10.1371/journal.pntd.0002651