Evaluation of the protective potential of aTaenia soliumcysticercus mimotope on murine cysticercosis

Highlights *Taenia soliumandTaenia crassicepsare phylogenetically related. * Synthetic mimotope ofT. solium(NC-1) conjugated to BSA was used as immunogen. * NC-1/BSA elicited protection to mice challenged intraperitoneally withT. crassiceps. * NC-1/BSA antibodies immunostained proteins fromT. crassi...

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Bibliographic Details
Published inVaccine Vol. 29; no. 51; p. 9473
Main Authors Capelli-Peixoto, Janaína, Chávez-Olórtegui, Carlos, Chaves-Moreira, Daniele, Minozzo, João Carlos, Gabardo, Juarez, Teixeira, Kádima Nayara, Thomaz-Soccol, van ete, Alvarenga, Larissa Magalhães, de Moura, Juliana
Format Journal Article
LanguageEnglish
Published Kidlington Elsevier Limited 28.11.2011
Subjects
Animals
Infections
Molecular weight
Parasites
Peptides
Proteins
Studies
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Summary:Highlights *Taenia soliumandTaenia crassicepsare phylogenetically related. * Synthetic mimotope ofT. solium(NC-1) conjugated to BSA was used as immunogen. * NC-1/BSA elicited protection to mice challenged intraperitoneally withT. crassiceps. * NC-1/BSA antibodies immunostained proteins fromT. crassicepscisticercus. * NC-1 is a good candidate to compose vaccine against human and animal cysticercosis.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.10.027