Studies on Immunostimulating Derivatives

In a search for potential immunomodulating agents novel pyrrolo[1, 2-c]pyrimidines were synthesized and their structures elucidated by spectroscopic means. Unfortunately, most of them were cytotoxic and devoid of effects on Tlymphocyte lymphoblastic transformation. Furthermore, they were inactive in...

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Published inChemical & pharmaceutical bulletin Vol. 39; no. 8; p. 2126
Main Authors Houssain BAHAJI, El, TRONCHE, Pierre, COUQUELET, Joele, HARRAGA, Said, PANOUSE-PERRIN, Jacqueline, RUBAT, Catherine
Format Journal Article
LanguageEnglish
Published Tokyo Japan Science and Technology Agency 01.08.1991
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Summary:In a search for potential immunomodulating agents novel pyrrolo[1, 2-c]pyrimidines were synthesized and their structures elucidated by spectroscopic means. Unfortunately, most of them were cytotoxic and devoid of effects on Tlymphocyte lymphoblastic transformation. Furthermore, they were inactive in the locomotor activity test in mice.
ISSN:0009-2363
1347-5223