A Multi-Fluorescent MDA435 Cell Line for Mitosis Inhibitor Studies

As a part of our efforts to create a pre-made multi-fluorescent cell library for various cytological assays, we made a triple-fluorescent cell line in which microtubules, chromosomes, and nuclear envelopes were visualized for simultaneous observation of spindle structure and chromosome distribution...

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Published inBioscience, biotechnology, and biochemistry Vol. 71; no. 10; p. 2603
Main Authors FUKADA, Takashi, SENDA-MURATA, Kaori, NISHIDA, Kumi, SAKAUSHI, Shinji, MINAMIKAWA, Harumi, DOTSU, Masaya, OKA, Shigenori, SUGIMOTO, Kenji
Format Journal Article
LanguageEnglish
Published Tokyo Oxford University Press 01.10.2007
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Summary:As a part of our efforts to create a pre-made multi-fluorescent cell library for various cytological assays, we made a triple-fluorescent cell line in which microtubules, chromosomes, and nuclear envelopes were visualized for simultaneous observation of spindle structure and chromosome distribution in living cells. Pilot experiments with microtubule-disturbing drugs showed the advantages of this cell line in mitosis inhibitor studies.
ISSN:0916-8451
1347-6947