Antimicrobial Photodynamic Therapy for Methicillin-Resistant Staphylococcus aureusInfection

Nowadays methicillin-resistant Staphylococcus aureus(MRSA) is one of the most common multidrug resistant bacteria both in hospitals and in the community. In the last two decades, there has been growing concern about the increasing resistance to MRSA of the most potent antibiotic glycopeptides. MRSA...

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Bibliographic Details
Published inBioMed research international Vol. 2013
Main Authors Xiu-jun Fu, Fang, Yong, Yao, Min
Format Journal Article
LanguageEnglish
Published New York Hindawi Limited 01.01.2013
Subjects
Antimicrobial agents
Apoptosis
Bacteria
Biomedical research
Deoxyribonucleic acid
DNA
Enzymes
Hospitals
Light
Lipids
Membranes
Molecular weight
Nosocomial infections
Photodynamic therapy
Proteins
Staphylococcus infections
Studies
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Summary:Nowadays methicillin-resistant Staphylococcus aureus(MRSA) is one of the most common multidrug resistant bacteria both in hospitals and in the community. In the last two decades, there has been growing concern about the increasing resistance to MRSA of the most potent antibiotic glycopeptides. MRSA infection poses a serious problem for physicians and their patients. Photosensitizer-mediated antimicrobial photodynamic therapy (PDT) appears to be a promising and innovative approach for treating multidrug resistant infection. In spite of encouraging reports of the use of antimicrobial PDT to inactivate MRSA in large in vitro studies, there are only few in vivo studies. Therefore, applying PDT in the clinic for MRSA infection is still a long way off.
ISSN:2314-6133
2314-6141
DOI:10.1155/2013/159157