Clinical evaluation of a novel 12-hole irrigated tip catheter ablation system for the treatment of typical atrial flutterâ[euro]"results from the Duo FLAIR clinical study

• Published in: Journal of interventional cardiac electrophysiology Vol. 37; no. 1; p. 97
• Main Authors: Lakkireddy, Dhanunjaya, Sangrigoli, Robert, Sloan, Stephen, Wiseman, Martin, Weiss, Raul, Molin, Frank, Kanaan, Nabil, Awasthi, Yashasvi, Mahapatra, Srijoy
• Format: Journal Article
• Language: English
• Published: New York Springer Nature B.V 01.06.2013
• ISSN: 1383-875X; 1572-8595
• DOI: 10.1007/s10840-012-9765-3

Higher current density at the proximal end of a six-hole catheter is not irrigated and thus could lead to uneven heating and possibly coagulum and charring. This study tested a novel 12-hole irrigated catheter with six additional holes at the proximal end that provides more uniform cooling during atrial flutter (AFL) ablation. A total of 188 patients (28 females, 66â[euro][per thousand]±â[euro][per thousand]11 years) were treated for typical AFL at 22 sites in the USA and Canada using Cool Path Duo at 50 W and 45 °C at an irrigation rate of 13 ml/min. The results were compared to historical data from an AFL study which used a six-hole catheter with similar design. A total of 2,725 RF lesions were applied in 188 patients with a mean RF duration of 18.2â[euro][per thousand]±â[euro][per thousand]11.7 min per procedure. Procedural success was achieved in 96.3 % (181 of 188) acutely and 98.3 % (173 of 176) patients at 3 months. Steam pops occurred in 0.6 % of lesions (15 of 2,725) without coagulum or charringâ[euro]¦ Compared to the six-hole irrigated tip catheter, the Cool Path Duo catheter delivered more power (33.8â[euro][per thousand]±â[euro][per thousand]5.9 vs. 29.7â[euro][per thousand]±â[euro][per thousand]5.2 W, pâ[euro][per thousand]<â[euro][per thousand]0.0001) at a lower average tip temperature (34.7â[euro][per thousand]±â[euro][per thousand]1.5 vs. 37.2â[euro][per thousand]±â[euro][per thousand]2.1 °C, pâ[euro][per thousand]<â[euro][per thousand]0.0001) with no statistical differences in either 3-month AFL recurrence or complications. Cool Path Duoâ"¢ irrigated tip catheter is safe and effective in treating typical AFL. When compared to a six-hole irrigated tip catheter, the Cool Path Duo catheter delivers more power at a lower temperature.[PUBLICATION ABSTRACT]