Cardioprotective effects of T3-146, a cyclic derivative of [gamma]-aminobutyric acid, under conditions of reperfusion
Intravenous injection of T3-146, a cyclic derivative of γ-aminobutyric acid (structural analog of piracetam), 5 min prior to reperfusion of the descendent branch of the left coronary artery prevents the development of serious rhythm disturbances and stabilizes hemodynamics and cardiac function. Thes...
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| Published in | Bulletin of experimental biology and medicine Vol. 124; no. 5; p. 1091 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Springer Nature B.V
01.11.1997
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Intravenous injection of T3-146, a cyclic derivative of γ-aminobutyric acid (structural analog of piracetam), 5 min prior to reperfusion of the descendent branch of the left coronary artery prevents the development of serious rhythm disturbances and stabilizes hemodynamics and cardiac function. These effects are probably due to the inhibitory effect of this compound on lipid peroxidation in the myocardium.[PUBLICATION ABSTRACT] |
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| AbstractList | Intravenous injection of T3-146, a cyclic derivative of γ-aminobutyric acid (structural analog of piracetam), 5 min prior to reperfusion of the descendent branch of the left coronary artery prevents the development of serious rhythm disturbances and stabilizes hemodynamics and cardiac function. These effects are probably due to the inhibitory effect of this compound on lipid peroxidation in the myocardium.[PUBLICATION ABSTRACT] |
| Author | Galenko-yaroshevskii, P A Uvarov, A V Turovaya, A Yu Popov, P B Kryzhanovskii, S A Khankoeva, A I |
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| DOI | 10.1007/BF02445670 |
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| Title | Cardioprotective effects of T3-146, a cyclic derivative of [gamma]-aminobutyric acid, under conditions of reperfusion |
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