Histomorphology of umbilical vessels at regions of low and high altitudes in Pakistan

To compare the histomorphological characteristics of human umbilical cord at high altitude (HA) area i.e. Skardu with those at low altitude (LA) i.e. Rawalpindi in Pakistan. This cross sectional comparative study was conducted in Anatomy department at Army Medical College Rawalpindi, from October 20...

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Published inPakistan journal of pathology : a journal of the Pakistan Association of Pathologists. Vol. 22; no. 3; p. 86
Main Authors Saga, Zarmina, Minhas, Liaqat Ali, Qamar, Khadija, Mubarik, Azhar
Format Journal Article
LanguageEnglish
Published Rawalpindi AsiaNet Pakistan (Pvt) Ltd 01.07.2011
Subjects
Altitude
Diabetes
Endothelium
Fetuses
Sea level
Stem cells
Veins & arteries
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Summary:To compare the histomorphological characteristics of human umbilical cord at high altitude (HA) area i.e. Skardu with those at low altitude (LA) i.e. Rawalpindi in Pakistan. This cross sectional comparative study was conducted in Anatomy department at Army Medical College Rawalpindi, from October 2002 to April 2003. Eighty umbilical cords, forty each from normal cases at LA and HA, were included. The full depth samples of umbilical cord were taken and stained with H & E. Detailed histomorphology of umbilical cord was studied and thickness of vessel walls was measured. Mean thickness of umbilical arteries in two groups was 630.73 ± 10.27 µm and 534.58 ± 8.17 µm, while mean thickness of umbilical vein in same groups was 365.55 ± 10.49 µm and 318.3 ± 8.64 µm respectively. The quantitative difference between mean thickness of umbilical arteries and veins, in LA and HA groups was statistically significant. The thickness of umbilical cord as well as umbilical vessels, was significantly less in HA group as compared to LA group.
ISSN:1024-6193