Improved [beta]-carotene biosynthesis and gene transcription in Blakeslea trispora with arachidonic acid

• Published in: Biotechnology letters Vol. 34; no. 11; p. 2107
• Main Authors: Hu, Xianmei, Sun, Jie, Yuan, Qipeng
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Nature B.V 01.11.2012
• Subjects: Biosynthesis; Biotechnology; Fermentation; Gene expression; Vitamin A

With 0.4 g l^sup -1^ arachidonic acid (AA) added to the medium after 36 h fermentation, β-carotene production in mated cultures of Blakeslea trispora was 73 % higher than that of the control at 690 mg l^sup -1^. With the treatment of AA, the transcriptional levels of genes hmgR, carRA and carB, that...