Improved [beta]-carotene biosynthesis and gene transcription in Blakeslea trispora with arachidonic acid
With 0.4 g l^sup -1^ arachidonic acid (AA) added to the medium after 36 h fermentation, β-carotene production in mated cultures of Blakeslea trispora was 73 % higher than that of the control at 690 mg l^sup -1^. With the treatment of AA, the transcriptional levels of genes hmgR, carRA and carB, that...
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Published in | Biotechnology letters Vol. 34; no. 11; p. 2107 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Dordrecht
Springer Nature B.V
01.11.2012
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Subjects | |
Online Access | Get full text |
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Summary: | With 0.4 g l^sup -1^ arachidonic acid (AA) added to the medium after 36 h fermentation, β-carotene production in mated cultures of Blakeslea trispora was 73 % higher than that of the control at 690 mg l^sup -1^. With the treatment of AA, the transcriptional levels of genes hmgR, carRA and carB, that are involved in carotene biosynthesis, increased by 31, 22 and 39 %, respectively.[PUBLICATION ABSTRACT] |
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ISSN: | 0141-5492 1573-6776 |
DOI: | 10.1007/s10529-012-1015-3 |