Semi-synthetic squalestatins:squalene synthase inhibition and antifungal activity. The sar of C6 and C7 modifications

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 3; no. 12; pp. 2605 - 2610
Main Authors GIBLIN, G. M. P, BELL, R, HANCOCK, A. P, HARTLEY, C. D, INGLIS, C. G. A, PAYNE, J. J, PROCOPIOU, P. A, SHINGLER, A. H, SMITH, C, SPOONER, S. J
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 1993
Subjects
Biological and medical sciences
General and cellular metabolism. Vitamins
Medical sciences
Pharmacology. Drug treatments
Rat
Enzyme
Rodentia
Enzyme inhibitor
In vitro
Fungi
Vertebrata
Antifungal agent
Mammalia
Enzymatic activity
Structure activity relation
Animal
Thallophyta
Antilipemic agent
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ISSN:0960-894X
1464-3405