Pneumocandin antifungal lipopeptides. The phenolic hydroxy is required for 1,3-β-glucan synthesis inhibition

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 3; no. 10
Main Authors BALKOVEC, J. M, BLACK, R. M, ABRUZZO, G. K, BARTIZAL, K, DREIKORN, S, NOLLSTADT, K
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 1993
Subjects
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Biological and medical sciences
Medical sciences
Pharmacology. Drug treatments
Candida albicans
Molecular structure
Enzyme
Transferases
Glycosyltransferases
Enzyme inhibitor
1,3-β-Glucan synthase
Biological activity
Fungi
Antifungal agent
Sensitivity resistance
Structure activity relation
Hexosyltransferases
Fungi Imperfecti
Chemical synthesis
Thallophyta
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ISSN:0960-894X
1464-3405