Synthesis of diblock functional poly(ε-capro)actone amphiphilic copolymers grafted with bioactive molecules and characterization of their micelles

• Published in: Polymer journal Vol. 45; no. 9; pp. 962 - 970
• Main Authors: HUANG, Yi-Ting, PENG, Kang-Yu, CHIU, Fang-Chyou, LEE, Ren-Shen
• Format: Journal Article
• Language: English
• Published: Avenel, NJ Nature Publishing Group 2013
• Subjects: Applied sciences; Biological and medical sciences; Exact sciences and technology; General pharmacology; Medical sciences; Organic polymers; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Physicochemistry of polymers; Polymers with particular properties; Preparation, kinetics, thermodynamics, mechanism and catalysts; Biological properties; 1,3-Dipolar cycloaddition; Triazole derivative copolymer; Indometacin; Propargylic compound; Chlorine containing copolymer; Cytotoxicity; Drug carrier; Caprolactone copolymer; Micellar critical concentration; Pyridine derivative copolymer; bioactive molecules; Amine copolymer; Release; Amphiphilic polymer; Lactone copolymer; Control release polymer; click chemistry; Experimental study; micelles; In vitro; Functional polymer; Non steroidal antiinflammatory agent; Azides; Alcohol copolymer; Chemical modification; graft-block functional polyester; amphiphilic; Preparation; Diblock copolymer; Kinetics; Aqueous solution; Nucleophilic substitution; Ring opening copolymerization
• ISSN: 0032-3896