Highly efficient and versatile synthesis of libraries of constrained β-strand mimetics Combinatorial chemistry

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 8; no. 17; pp. 2321 - 2326
Main Authors OGBU, C. O, QABAR, M. N, NAKANISHI, H, FUQIANG RUAN, BOLONG CAO, MINARIK, R, LITTLE, T, NELSON, S, MINH NGUYEN, GALL, A, KAHN, M, BOATMAN, P. D, URBAN, J, MEARA, J. P, FERGUSON, M. D, TULINSKY, J, LUM, C, BABU, S, BLASKOVICH, M. A
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 1998
Subjects
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Medical sciences
Pharmacology. Drug treatments
Molecular rigidity
Ketoamide
Serine endopeptidases
Enzyme
Angular nitrogen heterocycle
Peptidomimetic compound
Enzyme inhibitor
Combinatorial chemistry
Diels Alder addition
Steric hindrance
Thrombin
In vitro
Peptidases
Imide
Trypsin
Aminoketone
Structure activity relation
Plasma kallikrein
Tryptase
Bicyclic compound
Dipeptides
Hydrolases
Solid phase
Chemical synthesis
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ISSN:0960-894X
1464-3405