High-throughput and simultaneous analysis of eight central-acting muscle relaxants in human plasma by ultra-performance liquid chromatography―tandem mass spectrometry in the positive and negative ionization modes : Biomedical Mass Spectrometry

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Bibliographic Details
Published inAnalytical and bioanalytical chemistry Vol. 400; no. 7; pp. 1959 - 1965
Main Authors OGAWA, Tadashi, HATTORI, Hideki, KANEKO, Rina, ITO, Kenjiro, IWAI, Masae, MIZUTANI, Yoko, ARINOBU, Tetsuya, ISHII, Akira, SENO, Hiroshi
Format Journal Article
LanguageEnglish
Published Heidelberg Springer 2011
Subjects
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Exact sciences and technology
General, instrumentation
Other chromatographic methods
Spectrometric and optical methods
Performance evaluation
Solid phase extraction
Plasma
Internal standard
Instrumentation
Dantrolene
Electrospray
Quadrupole spectrometer
LC-MS/MS
Target
Accuracy
Detection limit
Standard curve
Pretreatment
Central-acting muscle relaxant
Monitoring
Trace analysis
Human
High-throughput
Sample
Liquid chromatography
Concentration
Chemical ionization
Analysis method
UPLC
Linearity
Mass spectrometry MS/MS
Quality control
Simultaneous measurement
Simultaneous reaction
Mass spectrometry
Carbamate
Interface
Signal to noise ratio
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ISSN:1618-2642
1618-2650