UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression

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Bibliographic Details
Published inAmerican journal of physiology. Regulatory, integrative and comparative physiology Vol. 69; no. 1
Main Authors BROMATI, Carla R, LELLIS-SANTOS, Camilo, YAMANAKA, Tatiana S, NOGUEIRA, Tatiane C. A, LEONELLI, Mauro, CAPERUTO, Luciana C, GORJAO, Renata, LETTER, Adriana R, ANHE, Gabriel F, BORDIN, Silvana
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 2011
Subjects
Biological and medical sciences
Endocrine pancreas
Fundamental and applied biological sciences. Psychology
Heart
Morphology. Functional localizations
Vertebrates: cardiovascular system
Vertebrates: endocrinology
Pancreatic hormone
Phosphorylation
Rat
Secretion
Rodentia
Akt protein kinase
Stimulation
β-cell apoptosis
Insulin
Unfolded protein response
Pregnancy
Vertebrata
Mammalia
Adenohypophyseal hormone
lactation
Burst
Early
β Cell
Adaptation
Apoptosis
Endocrine pancreas
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ISSN:0363-6119
1522-1490