Design, synthesis, and testing of an 6-0-linked series of benzimidazole based inhibitors of CDK5/p25

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Bibliographic Details
Published inBioorganic & medicinal chemistry Vol. 19; no. 1; pp. 359 - 373
Main Authors JAIN, Prashi, FLAHERTY, Patrick T, SHUYAN YI, CHOPRA, Ishveen, BLEASDELL, Gwenyth, LIPAY, Josh, FERANDIN, Yoan, MEIJER, Laurent, MADURA, Jeffry D
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier 2011
Subjects
Biological and medical sciences
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
1-Isopropyl benzimidazole
Ether
Enzyme
Transferases
Modeling
Biological activity
Cyclin-dependent kinase
CDK5
Benzimidazole derivatives
Benzimidazole
Molecular model
Inhibitor
Chemical synthesis
Cyclin dependent kinase
Secondary amine
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ISSN:0968-0896
1464-3391