Metabolic activation capacity by primary hepatocytes expands the applicability of the embryonic stem cell test as alternative to experimental animal testing ReProTect

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Bibliographic Details
Published inReproductive toxicology (Elmsford, N.Y.) Vol. 30; no. 1; pp. 113 - 120
Main Authors HETTWER, Michael, REIS-FERNANDES, Marcos A, IKEN, Marcus, OTT, Michael, STEINBERG, Pablo, NAU, Heinz
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier 2010
Subjects
Biological and medical sciences
Embryology: invertebrates and vertebrates. Teratology
Fundamental and applied biological sciences. Psychology
Medical sciences
Teratology. Teratogens
Toxicology
Alternative test method
Digestive system
Liver
Stem cell
Proteratogen
Experimental animal
Medical screening
In vitro
Mixed cell culture
Hepatocyte
Embryonic cell
Primary
Metabolic activation
Test method
Alternative method
Co-culture
Embryonic stem cell test
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ISSN:0890-6238
1873-1708